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Subutex and Suboxone are very safe when administered by physician who is specially trained in detoxification. Subutex and Suboxone have been studied in over 2 000 patients and shown to be safe and effective treatments for opiate dependence. Side effects usually peak in the beginning of treatment with Subutex or Suboxone. Clinical data indicates that health risks associated with detox are less with buprenorphine than other opioids used in detox. Buprenorphine is considered to have less risk for causing psychological and or physical dependence than the drugs in Schedule II such as morphine oxycodone fentanyl or methadone. Under the care of a Dr. Nathan the side effect of Subutex and Suboxone detoxification can be greatly reduced.